Viability of autologous fascia lata in heart valve replacements

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Viability of autologous fascia lata in heart valve replacements.

A histological and radioautographic examination of 11 autologous fascia lata heart valves used in man is described. There was a significant decrease, exponential with time, in the number of fibroblasts per unit volume (P<0 001). The collagen bundles were grossly disorganized and separated, suggesting a breakdown of the cross-linkage in the tissue. Redundant connective tissue on the surface of t...

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Autologous fascia lata for heart valve replacement.

To obviate the drawbacks of prosthetic devices and in search of a better substitute for diseased heart valves a technique of using autologous fascia lata grafts attached to a support frame was developed. The technique of preparing mounted fascia lata grafts is briefly outlined and their surgical implantation into the mitral, tricuspid, and aortic areas is described. Since April 1969, 83 fascial...

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Autologous fascia lata cardiac valve replacement.

Prosthetic cardiac valve replacement has been carried out at Brugmann University Hospital since 1962. In a series of 370 valvular replacements, operative and hospital deaths have attained a low rate (5%). The overall survival of 70% is comparable to that of most published series. Late thromboembolic complications, in spite of longterm anticoagulant therapy, remain the principal disadvantage of ...

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Aortic valve replacement with frame - mounted autologous fascia lata

Between June 1969 and August I970, 8o patients, aged 22 to 63 years, had lone aortic valve replacement with frame-mounted autologous fascia lata. The operative mortality was 3.8 per cent. Seventy-seven survivors have been followed for 3 to 4 years and 50 have had postoperative investigation. There have been 8 subsequent deaths, 3 from infective endocarditis, 4 from aortic regurgitation, and one...

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Autologous fascia lata transplantation for heart valve replacement. A two-year experience at the National Heart Hospital, London.

patients underwent 262 valve replacements with frame-mounted autologous fascia lata valves in the aortic, mitral, and/or tricuspid positions at the National Heart Hospital. A single fascia lata valve was inserted in 146 patients and multi-valve replacement was performed in 55 instances. Hospital and late mortality are comparable with that following other procedures of heart valve replacement. O...

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ژورنال

عنوان ژورنال: Thorax

سال: 1971

ISSN: 0040-6376

DOI: 10.1136/thx.26.3.277